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Metabolic studies in human participants
We use the "BOD POD" to measure body composition based on air displacement in our subjects in clinical metabolic studies. The device is located in the Metabolic Core Unit of the Center of Brain Behavior and Metabolism (CBBM).
Thermogenesis studies in animal models
With our infrared camera we measure the thermogenesis of mice in the brown fat tissue in the neck of the animals in a non-contact and non-invasive way. In addition, we can determine heat release via tail temperature.
Studies at the cellular level
We study the molecular mechanisms of various metabolic or endocrine processes at the cellular level. Here, we use established cell lines, primary cell cultures or tissue sections, such as the group of parvalbuminergic neurons in the brain shown here.
Welcome to the website of the Institute of Endocrinology and Diabetes
The Institute of Endocrinology and Diabetes was founded by the University of Lübeck in 2020 to give the research fields of endocrinology and diabetes more independence and improved national and international visibility.
The institute is headed by the two directors Prof. Dr. med. Sebastian Meyhöfer and Prof. Dr. rer. nat. Jens Mittag. The overall goal of the institute is to interlink clinical, metabolic and endocrine studies in human participants with basic research in diverse in vivo and in vitro model systems. This not only increases the translational relevance of the study results, but also allows the underlying molecular mechanisms to be elucidated, which contributes to a better understanding of the processes and can thus actively open up new therapeutic options.
The department of "Clinical Endocrinology", headed by Prof. Meyhöfer, is primarily concerned with possible therapeutic approaches to obesity and diabetes.
The department "Molecular Endocrinology" headed by Prof. Mittag investigates the effect of thyroid hormones on the cardiovascular system, the regulation of body temperature and the central nervous system. Here, the main focus is on a newly discovered population of hypothalamic neurons that regulate blood pressure and heart rate in a temperature-dependent manner and are primarily dependent on maternal thyroid hormones during their development in the embryo. The research group thus works in an interdisciplinary manner at the interface of endocrinology with physiology, cardiology, neurology and pediatrics.
We hope you enjoy exploring our pages!
